Neutrophil gelatinase-associated lipocalin as an early indicator for postoperative renal failure

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Comparative Assessment of Neutrophil Gelatinase-Associated Lipocalin (NGAL) and Cystatin C as Early Biomarkers for Early Detection of Renal Failure in Patients with Hypertension

Background: Hypertension is one the most common causes of chronic kidney disease (CKD). One of the major concerns in hypertensive patients is early detection of renal disorders. In the past, serum creatinine (Scr) concentration was used as a marker of kidney function, but it proffers a late reflection of reduced glomerular filtration rate. Cystatin C and neutrophil gelatinase-associated lipocal...

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assessment of neutrophil gelatinase-associated lipocalin (ngal) as an early biomarker for detection of renal impairment in hypertensive patients

chronic kidney disease (ckd) is probably the most important problem of public health in advanced countries. kidneys are often damaged as a result of high blood pressure. one of our main concerns in patients with hypertension is early detection of kidney disorders. the routine biomarkers such as creatinine have some limitation for this purpose, however recent studies suggest plasma ngal to be a ...

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Identification of neutrophil gelatinase-associated lipocalin as a novel early urinary biomarker for ischemic renal injury.

Acute renal failure (ARF) secondary to ischemic injury remains a common and potentially devastating problem. A transcriptome-wide interrogation strategy was used to identify renal genes that are induced very early after renal ischemia, whose protein products might serve as novel biomarkers for ARF. Seven genes that are upregulated >10-fold were identified, one of which (Cyr61) has recently been...

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Neutrophil gelatinase-associated lipocalin as a biomarker for lupus nephritis.

BACKGROUND One of the challenges of treating patients with lupus nephritis (LN) is to accurately assess disease activity and predict its outcome. Since renal-biopsy cannot be performed routinely, new surrogate biomarkers are needed. METHODS We evaluated neutrophil gelatinase-associated lipocalin (NGAL), to predict renal outcome in LN. Serum and urinary NGAL levels, measured by the enzyme-link...

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comparative assessment of neutrophil gelatinase-associated lipocalin (ngal) and cystatin c as early biomarkers for early detection of renal failure in patients with hypertension

background: hypertension is one the most common causes of chronic kidney disease (ckd). one of the major concerns in hypertensive patients is early detection of renal disorders. in the past, serum creatinine (scr) concentration was used as a marker of kidney function, but it proffers a late reflection of reduced glomerular filtration rate. cystatin c and neutrophil gelatinase-associated lipocal...

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ژورنال

عنوان ژورنال: Critical Care

سال: 2010

ISSN: 1364-8535

DOI: 10.1186/cc8759